Rehabilitation may be required at any point of the care pathway from preparing for treatment through to disease-free survival and palliative care.

Evaluation for postoperative rehabilitation is recommended for all patients with extremity sarcoma (NCCN 2016a, NCCN 2016b). Amputees should be referred to a specialist physiotherapist for a comprehensive rehabilitation program. Rehabilitation should be continued until maximum function is achieved (NCCN 2016a) and should be highly integrated with the treating medical team.

Other issues that may need to be addressed include managing cancer-related fatigue, cognitive changes, improving physical endurance, achieving independence in daily tasks, returning to work and ongoing adjustment to disease and its sequelae.