Preventing significant liver disease and fibrosis is the key to decreasing the risk of recurrent tumours. Tumours often develop due to a field effect throughout the liver, so preventing new tumours or recurrence is difficult.

Not smoking, eating a healthy diet, being sun smart, avoiding or limiting alcohol intake, being physically active and maintaining a healthy body weight may help reduce the risk of primary recurrence or a second primary cancer.

Continuing to manage underlying conditions may also help reduce the risk of secondary recurrence.

Encourage and support all cancer survivors to reduce modifiable risk factors for recurrence as well as other chronic diseases. Ongoing coordination of care between providers should also deal with any comorbidities, particularly ongoing complex and life-threatening comorbid conditions.