1.2 Risk factors
Risk factors for bone sarcoma may include:
- family history (slight increased risk)
- history of retinoblastoma
- Li-Fraumeni syndrome
- history of childhood cancer
- prior abnormalities such as Paget’s disease, avascular necrosis or polyostotic fibrous dysplasia
- past treatment with chemotherapy or radiation therapy
- exposure to certain chemicals (for example, vinyl chloride and dioxin)
- age: adolescent/young adult (less than 30) or over 50 years.
Risk factors for soft tissue sarcoma include:
- familial syndromes
- history of cancer
- past treatment with radiation therapy
- prolonged lymphoedema
- exposure to certain chemicals (for example, vinyl chloride and dioxin)
- age (over 50 years).