Staging and prognostic assessment are critical elements in treatment planning and should be clearly documented in the patient’s medical record. The burden of disease at baseline, including the degree of bone marrow involvement, any evidence of end-organ damage and prognostic parameters, should be clearly documented in the patient’s medical record.

The most widely accepted prognostic model for MM is the Revised International Staging System (R-ISS). This incorporates the presence of high-risk genetic lesions based on cytogenetics and/or FISH, and the level of beta-2 microglobulin, albumin and LDH (IMF 2019).

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For more information visit the Myeloma Australia website .