2.1 Signs and symptoms

2.1 Signs and symptoms

The following signs and symptoms should be investigated:

  • vaginal bleeding after menopause
  • bleeding between periods
  • abnormal, watery or blood-tinged vaginal discharge
  • unexplained weight loss
  • pelvic pain
  • difficult or painful urination.

The presence of multiple signs and symptoms, particularly in combination with other underlying risk factors, indicates an increased risk of endometrial cancer. However, the presence of these symptoms may be due to other conditions.

  • Any bleeding or abnormal vaginal discharge after menopause (more than 12 months after the last period) should be investigated without delay.
  • Any new, persistent or progressive symptoms in patients over the age of 40 should be investigated within four weeks of presenting with symptoms.
  • Symptoms that do not respond to treatment initiated by the general practitioner (e.g. oral contraception or progesterone) should be evaluated within three months of treatment beginning.