STEP 1: Prevention and early detection

Prevention: The causes of sarcoma are not fully understood, and there is currently no clear prevention strategy.

Risk factors:

Risk factors for bone sarcoma include:

  • family history
  • history of retinoblastoma
  • Li-Fraumeni syndrome
  • history of childhood cancer
  • prior abnormalities (for example, Paget’s disease, avascular necrosis, polyostotic fibrous dysplasia).
  • past treatment with chemotherapy or radiation therapy
  • exposure to certain chemicals (for example, vinyl chloride and dioxin)
  • age (less than 30 or over 50 years).

Risk factors for soft tissue sarcoma include:

  • familial syndromes
  • history of cancer
  • past treatment with radiation therapy
  • prolonged lymphoedema
  • exposure to certain chemicals (for example, vinyl chloride and dioxin)
  • age (over 50 years).