Treatment will depend on the, extent of relapsed or progressive disease, previous management and the patient’s preferences.

In managing people with relapsed or progressive MDS, treatment may include these options:

• clinical trials
• treatment for AML if there is progression to AML, if clinically appropriate
• supportive medical management
• palliative

The potential goals of treatment should be discussed, respecting the patient’s cultural values. Wherever possible, written information should be provided.

Encourage early referral to clinical trials or accepting an invitation to participate in research.